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Apomorphine injections: Predictors of initial common adverse events and long term tolerability
27 January 2012
William G. Ondo, Christine Hunter, Joseph M. Ferrara, Giovanni Mostile
Abstract: Background: Apomorphine injections effectively abort “off” episodes in Parkinson’s disease (PD). However, their use is limited by actual and perceived adverse events (AE). To our knowledge, ...
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Magnetization transfer and adiabatic R1ρ MRI in the brainstem of Parkinson’s disease
20 January 2012
Paul J. Tuite, Silvia Mangia, Andrew E. Tyan, Michael K. Lee, Michael Garwood, Shalom Michaeli
Abstract: Background: In addition to classic midbrain pathology, Parkinson’s disease (PD) is accompanied by changes in pontine and medullary brainstem structures. These additional abnormalities may un...
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Falling short: Underestimation of fracture risk in atypical parkinsonian syndromes
20 January 2012
Alison J. Yarnall, Gordon W. Duncan, Tien K. Khoo, David J. Burn
Falls are a prominent feature of progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). Falls and osteoporosis are common in the older population with up to 30% of the community dwell...
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Movement orientation switching with the eyes and lower limb in Parkinson disease
20 January 2012
Corey A. Lohnes, Gammon M. Earhart
Abstract: Difficulty switching between motor programs is a proposed cause of motor blocks in Parkinson disease (PD). Switching from one movement to another has been studied in the upper extremity and ...
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Genetic analysis of HLA-DRA region variation in Taiwanese Parkinson’s disease
13 January 2012
Han-Lin Chiang, Guey-Jen Lee-Chen, Chiung Mei Chen, Yi-Chun Chen, Chei-Mei Lee, Ming-Hui Liao, Yih-Ru Wu
Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder comprising both motor and cognitive disability. The pathogenesis of the disease is still unclear; however, neuroinflammation seemed t...
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