Parkinsonism & Related Disorders
Volume 11, Issue 1 , Pages 35-38, January 2005

Body mass index is reduced early in Parkinson's Disease

Department of Neurology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA

Received 30 March 2004; received in revised form 8 July 2004; accepted 8 July 2004.

Abstract 

Mean body mass index (BMI) in 100 cases of idiopathic Parkinson's disease (PD) was found to be 9% reduced in comparison to that in patients with either essential tremor or no neurologic disease. A similar reduction in BMI was also discovered among the 24 cases of PD in whom retrospective BMI data were available from their presymptomatic years. These results suggest that alterations in nutrient intake or metabolism could reflect early changes in the central autonomic network preceding the emergence of classical extrapyramidal manifestations of PD.

Keywords: Body mass index, Weight loss, Parkinson's disease

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PII: S1353-8020(04)00115-4

doi:10.1016/j.parkreldis.2004.07.001

Parkinsonism & Related Disorders
Volume 11, Issue 1 , Pages 35-38, January 2005