Pisa syndrome as a motor complication of Parkinson's disease

Kim, Joong-Seok; Park, Jeong-Wook; Chung, Sung-Woo; Kim, Yeong-In; Kim, Hee-Tae; Lee, Kwang-Soo

doi:10.1016/j.parkreldis.2006.03.010

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Volume 13, Issue 2 , Pages 126-128, March 2007

Pisa syndrome as a motor complication of Parkinson's disease

Joong-Seok Kim
- Department of Neurology, The Catholic University of Korea, Republic of Korea
Jeong-Wook Park
- Department of Neurology, The Catholic University of Korea, Republic of Korea
Sung-Woo Chung
- Department of Neurology, The Catholic University of Korea, Republic of Korea
Yeong-In Kim
- Department of Neurology, The Catholic University of Korea, Republic of Korea
Hee-Tae Kim
- Department of Neurology, College of Medicine, Hanyang University, Republic of Korea
Kwang-Soo Lee
- Department of Neurology, The Catholic University of Korea, Republic of Korea
- Corresponding author. Department of Neurology, Kangnam St. Mary Hospital, #505, Banpodong, Seochogu, Seoul, 137-701, Republic of Korea. Tel.: +8225902091; fax: +8225999686.

Received 25 January 2006; received in revised form 21 March 2006; accepted 27 March 2006.

Abstract

We describe two elderly patients with a convincing clinical diagnosis of Parkinson's disease (PD) who developed axial end-of-dose/off dystonia, also referred to as Pisa syndrome (PS). The worsening of symptoms in the “off” period, and a favorable response of the dystonia to an increase of levodopa suggests that PS in our patients may be primarily related to a manifestation of motor fluctuations in PD.

Keywords: Pisa syndrome, Parkinson's disease, Motor complication