Assessing health-related quality of life in patients with Parkinson's disease in a prospective longitudinal study

Reuther, M.; Spottke, E.A.; Klotsche, J.; Riedel, O.; Peter, H.; Berger, K.; Athen, O.; Köhne-Volland, R.; Dodel, R.C.

doi:10.1016/j.parkreldis.2006.07.009

« Previous Next »Parkinsonism & Related Disorders
Volume 13, Issue 2 , Pages 108-114, March 2007

Assessing health-related quality of life in patients with Parkinson's disease in a prospective longitudinal study

M. Reuther
- Department of Neurology, Philipps-University Marburg, Germany
E.A. Spottke
- Friedrich-Wilhelms-University, Bonn, Germany
J. Klotsche
- Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden, Germany
O. Riedel
- Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden, Germany
H. Peter
- Department of Neurology, Philipps-University Marburg, Germany
K. Berger
- MERG, Medical Economics Research Group, München, Germany
O. Athen
- Metronomia, München, Germany
R. Köhne-Volland
- Metronomia, München, Germany
R.C. Dodel
- Department of Neurology, Philipps-University Marburg, Germany
- Friedrich-Wilhelms-University, Bonn, Germany
- Corresponding author. Department of Neurology, Philipps-University Marburg, Rudolf-Bultmannstr. 8, 35039 Marburg, Germany. Tel.: +4964212865606; fax: +4964212865606.

Received 31 January 2006; received in revised form 11 July 2006; accepted 13 July 2006.

Abstract

Objective

To prospectively assess the health-related quality of life (HrQoL) in Parkinson's disease (PD) during 12 months.

Methods

HrQoL was assessed in 145 PD patients using the PD-specific PDQ-39, PDQL and the generic EQ-5D. In addition, clinical rating-scales were used.

Results

All scales showed a pronounced effect of PD. In comparison to an age-matched population the EQ-5D was considerably affected. In comparison to baseline, however, there was no significant change in the generic scale but a significant change in the sum-score of disease-specific HrQoL-scales.