Parkinsonism & Related Disorders
Volume 13, Issue 7 , Pages 434-437, October 2007

Gait disturbance in normal pressure hydrocephalus: A clinical study

  • Paulo Bugalho

      Affiliations

    • Neurology Department–Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019, Lisboa, Portugal
    • Corresponding Author InformationCorresponding author. Tel.: +351213650459; fax: +351213420155.
    • ,
  • João Guimarães

      Affiliations

    • Neurology Department–Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019, Lisboa, Portugal
    • Faculty of Medical Sciences, Lisbon, Portugal

Received 26 April 2006; received in revised form 20 June 2006; accepted 18 August 2006.

Abstract 

The origin of gait disturbance in normal pressure hydrocephalus (NPH) is poorly understood. We assessed the frequency of frontal and sub-cortical hypokinetic gait clinical features and changes in gait variables after lumbar puncture (LP), in 15 patients with idiopathic NPH. Hypokinesia and disequilibrium were the main features, suggesting dysfunction of the basal ganglia (BG) and the frontal lobe (FL), respectively. Disequilibrium responded worse to LP and frontal signs were more frequent in patients that did not improve after LP. This could be related to earlier disturbance of frontal gait control.

Keywords: Normal pressure hydrocephalus, Gait, Lumbar puncture, Disequilibrium, Hypokinesia

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1353-8020(06)00217-3

doi:10.1016/j.parkreldis.2006.08.007

Parkinsonism & Related Disorders
Volume 13, Issue 7 , Pages 434-437, October 2007

Article Tools