Parkinsonism & Related Disorders
Volume 13, Issue 7 , Pages 438-442 , October 2007

The time course of the return of upper limb bradykinesia after cessation of subthalamic stimulation in Parkinson's disease

  • Zoltan Keresztenyi

      Affiliations

    • Department of Neurology, Ludwig-Maximilians University, Munich, Germany
    • Department of Biomechanics, Semmelweis University, Budapest, Hungary
    • Both authors contributed equally to this paper.
    • ,
  • Peter Valkovič

      Affiliations

    • Department of Neurology, Ludwig-Maximilians University, Munich, Germany
    • 2nd Department of Neurology, Comenius University, Bratislava, Slovakia
    • Both authors contributed equally to this paper.
    • ,
  • Thomas Eggert

      Affiliations

    • Department of Neurology, Ludwig-Maximilians University, Munich, Germany
    • ,
  • Ulrich Steude

      Affiliations

    • Department of Neurosurgery, Ludwig-Maximilians University, Munich, Germany
    • ,
  • Joachim Hermsdörfer

      Affiliations

    • Clinical Neuropsychology Research Group, Hospital München-Bogenhausen, Munich, Germany
    • ,
  • Jozsef Laczko

      Affiliations

    • Department of Biomechanics, Semmelweis University, Budapest, Hungary
    • ,
  • Kai Bötzel

      Affiliations

    • Department of Neurology, Ludwig-Maximilians University, Munich, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +498970953673; fax: +498970953677.

Received 22 March 2006 ,Revised 27 November 2006 ,Accepted 10 December 2006.

References 

  1. Deuschl G, Schade-Brittinger C, Krack P, Volkmann J, Schafer H, Bötzel K, et al. A randomized trial of deep-brain stimulation for Parkinson's disease. N Engl J Med. 2006;355:896–908
  2. Lopiano L, Torre E, Benedetti F, Bergamasco B, Perozzo P, Pollo A, et al. Temporal changes in movement time during the switch of the stimulators in Parkinson's disease patients treated by subthalamic nucleus stimulation. Eur Neurol. 2003;50:94–99
  3. Fahn S, Elton RL. Committee MotUD: unified Parkinson's Disease Rating Scale. In:  Fahn S,  Marsden CD,  Calne D,  Goldstein M editor. Recent developments in Parkinson's disease. Florham Park, NJ: MacMillan Health Care Information; 1987;p. 153–163
  4. Machado A, Rezai AR, Kopell BH, Gross RE, Sharan AD, Benabid AL. Deep brain stimulation for Parkinson's disease: surgical technique and perioperative management. Mov Disord. 2006;21(Suppl. 14):S247–S258
  5. Hermsdorfer J, Marquardt C, Wack S, Mai N. Comparative analysis of diadochokinetic movements. J Electromyogr Kinesiol. 1999;9:283–295
  6. Faist M, Xie J, Kurz D, Berger W, Maurer C, Pollak P, et al. Effect of bilateral subthalamic nucleus stimulation on gait in Parkinson's disease. Brain. 2001;124:1590–1600
  7. Boraud T, Tison F, Gross C. Quantification of motor slowness in Parkinson's disease: correlations between the tapping test and single joint ballistic movement parameters. Parkinsonism Relat Disord. 1997;3:47–50
  8. Temperli P, Ghika J, Villemure JG, Burkhard PR, Bogousslavsky J, Vingerhoets FJ. How do Parkinsonian signs return after discontinuation of subthalamic DBS?. Neurology. 2003;60:78–81
  9. Meissner W, Paul G, Reum T, Reese R, Sohr R, Morgenstern R, et al. The influence of pallidal deep brain stimulation on striatal dopaminergic metabolism in the rat. Neurosci Lett. 2000;296:149–152
  10. Agostino R, Berardelli A, Curra A, Accornero N, Manfredi M. Clinical impairment of sequential finger movements in Parkinson's disease. Mov Disord. 1998;13:418–421
  11. Schenk T, Baur B, Steude U, Bötzel K. Effects of deep brain stimulation on prehensile movements in PD patients are less pronounced when external timing cues are provided. Neuropsychologia. 2003;41:783–794
  12. Wenzelburger R, Kopper F, Zhang BR, Witt K, Hamel W, Weinert D, et al. Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements. Mov Disord. 2003;18:1162–1169

PII: S1353-8020(06)00289-6

doi: 10.1016/j.parkreldis.2006.12.003

Parkinsonism & Related Disorders
Volume 13, Issue 7 , Pages 438-442 , October 2007

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