Paroxysmal dyskinesia with interictal myoclonus and dystonia: A report of two cases

De Grandis, Elisa; Mir, Pablo; Edwards, Mark J.; Quinn, Niall P.; Bhatia, Kailash P.

doi:10.1016/j.parkreldis.2007.03.005

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Volume 14, Issue 3 , Pages 250-252, April 2008

Paroxysmal dyskinesia with interictal myoclonus and dystonia: A report of two cases

Elisa De Grandis
- Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
- Operative Unit of Child Neuropsychiatry, Department of Neurosciences, Ophthalmology and Genetics, G Gaslini Institute, University of Genoa, L.go Gaslini 5, 16148 Genoa, Italy
Pablo Mir
- Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
- Servicio de Neurología, Hospital Universitario Virgen del Rocío, Seville, Spain
Mark J. Edwards
- Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
Niall P. Quinn
- Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
Kailash P. Bhatia
- Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
- Corresponding author. Tel.: +442078373611x4253; fax: +442076762175.

Received 1 November 2006; received in revised form 20 March 2007; accepted 29 March 2007.

Abstract

Idiopathic paroxysmal dyskinesias (PxD) are characterized by attacks of hyperkinetic movement, with no inter-ictal symptoms. We report two cases, one with paroxysmal kinesigenic dyskinesia and another with paroxysmal exercise-induced dystonia, both of whom had myoclonus and dystonia between attacks. This previously unreported association highlights the heterogeneity of paroxysmal movement disorders.

Keywords: Paroxysmal dyskinesias, Exercise-induced, Kinesigenic, Myoclonus-dystonia, Myoclonus, Dystonia.