Parkinsonism & Related Disorders
Volume 14, Issue 3 , Pages 250-252 , April 2008

Paroxysmal dyskinesia with interictal myoclonus and dystonia: A report of two cases

  • Elisa De Grandis

      Affiliations

    • Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    • Operative Unit of Child Neuropsychiatry, Department of Neurosciences, Ophthalmology and Genetics, G Gaslini Institute, University of Genoa, L.go Gaslini 5, 16148 Genoa, Italy
    • ,
  • Pablo Mir

      Affiliations

    • Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    • Servicio de Neurología, Hospital Universitario Virgen del Rocío, Seville, Spain
    • ,
  • Mark J. Edwards

      Affiliations

    • Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    • ,
  • Niall P. Quinn

      Affiliations

    • Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    • ,
  • Kailash P. Bhatia

      Affiliations

    • Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    • Corresponding Author InformationCorresponding author. Tel.: +442078373611x4253; fax: +442076762175.

Received 1 November 2006 ,Revised 20 March 2007 ,Accepted 29 March 2007.

References 

  1. Bhatia KP. Familial (idiopathic) paroxysmal dyskinesia: an update. Sem Neurol. 2001;21:69–74
  2. Bhatia KP, Soland VL, Bhatt MH, Quinn NP, Marsden DC. Paroxysmal exercise-induced dystonia: eight new sporadic cases and a review of the literature. Mov Disord. 1997;12:1007–1012
  3. Demirkiran M, Jankovic J. Paroxysmal dyskinesias: clinical features and classification. Ann Neurol. 1995;38:571–579
  4. Guerrini R, Bonanni P, Nardocci N, Parmeggiani L, Piccirilli M, De Fusco M, et al. Autosomal recessive rolandic epilepsy with paroxysmal exercise-induced dystonia and writer's cramp: delineation of the syndrome and gene mapping to chromosome 16p12-11.2. Ann Neurol. 1999;45:344–352
  5. Auburger G, Ratzlaff T, Lunkes A, Nelles HW, Leube B, Binkofski F, et al. A gene for autosomal dominant paroxysmal choreoathetosis/spasticity (CSE) maps to the vicinity of a potassium channel gene cluster on chromosome 1p, probably within 2 cM between D1S443 and D1S197. Genomics. 1996;31:90–94
  6. Cochen De Cock V, Bourdain F, Apartis E, Trocello JM, Roze E, Vidailhet M. Interictal myoclonus with paroxysmal kinesigenic dyskinesia. Mov Disord. 2006;21:1533–1535
  7. Quinn NP. Essential myoclonus and myoclonic dystonia. Mov Disord. 1996;11:119–124
  8. Valente EM, Edwards MJ, Mir P, DiGiorgio A, Salvi S, Davis M, et al. The epsilon-sarcoglycan gene in myoclonic syndromes. Neurology. 2005;64:737–739
  9. Pourfar MH, Guerrini R, Parain D, Frucht SJ. Classification conundrums in paroxysmal dyskinesias: a new subtype or variations on classic themes?. Mov Disord. 2005;20:1047–1051

PII: S1353-8020(07)00067-3

doi: 10.1016/j.parkreldis.2007.03.005

Parkinsonism & Related Disorders
Volume 14, Issue 3 , Pages 250-252 , April 2008

Article Tools