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Volume 15, Issue 1, Pages 41-46 (January 2009)


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Smoking and tea consumption delay onset of Parkinson's disease

Boris Kandinova, Nir Giladibcemail address, Amos D. KorczynabcCorresponding Author Informationemail address

Received 19 July 2007; received in revised form 5 January 2008; accepted 18 February 2008.

Abstract 

Cigarette smoking, coffee and tea drinking may protect against Parkinson's disease (PD). These factors were assessed, retrospectively, to measure their effect on the age of PD onset. The study population consisted of 278 consecutive PD patients. Smoking ≥10 pack-years delayed age of PD onset by 3.2 years (p<0.05). Consumption of tea more than 3 cups per day delayed age of motor symptoms onset by 7.7 years (p<0.01). Coffee consumption exceeding 3 cups per day advanced the age of PD onset by 4.8 years (p=0.03). Thus, tea consumption and smoking can delay the age of PD onset, while coffee drinking may have the opposite effect.

a Department of Physiology and Pharmacology, Tel Aviv University, Tel Aviv, Israel

b Department of Neurology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

c Department of Neurology, Sourasky Medical Center, Tel Aviv, Israel

Corresponding Author InformationCorresponding author. Department of Physiology and Pharmacology, Sieratzki Chair of Neurology, Tel Aviv University, Ramat Aviv 69978, Israel. Tel.: +972 3 6974229; fax: +972 3 6409113.

PII: S1353-8020(08)00093-X

doi:10.1016/j.parkreldis.2008.02.011


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