Parkinsonism & Related Disorders
Volume 16, Issue 3 , Pages 153-162 , March 2010

Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies

  • Takashi Morishita

      Affiliations

    • Department of Neurology, University of Florida College of Medicine/Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL, USA
    • Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan
  • ,
  • Kelly D. Foote

      Affiliations

    • Department of Neurosurgery, University of Florida College of Medicine/Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL, USA
  • ,
  • Adam P. Burdick

      Affiliations

    • Department of Neurosurgery, University of Florida College of Medicine/Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL, USA
  • ,
  • Yoichi Katayama

      Affiliations

    • Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan
    • Division of Applied System Neuroscience, Department of Advanced Medical Science, Nihon University School of Medicine, Tokyo, Japan
  • ,
  • Takamitsu Yamamoto

      Affiliations

    • Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan
    • Division of Applied System Neuroscience, Department of Advanced Medical Science, Nihon University School of Medicine, Tokyo, Japan
  • ,
  • Steven J. Frucht

      Affiliations

    • Department of Neurology, Columbia University College of Physicians and Surgeons/Columbia-Presbyterian Medical Center, New York, NY, USA
  • ,
  • Michael S. Okun

      Affiliations

    • Department of Neurology, University of Florida College of Medicine/Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL, USA
    • Department of Neurosurgery, University of Florida College of Medicine/Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL, USA
    • Corresponding Author InformationCorresponding author at: Department of Neurology, McKnight Brain Institute, Medical Director National Parkinson Foundation, 100 S Newell Dr, Room L3-101, Gainesville, FL 32610, USA. Tel.: +1 352 273 5550; fax: +1 352 273 5575.

Received 30 June 2009 ,Revised 23 September 2009 ,Accepted 1 October 2009.

References 

  1. Anderson WS, Lenz FA. Surgery insight: deep brain stimulation for movement disorders. Nat Clin Pract Neurol. 2006;2:310–320
  2. Hariz MI. Psychosurgery, deep brain stimulation, and the re-writing of history. Neurosurgery. 2008;63:E820;author reply E820
  3. Hooper AK, Ellis TM, Foote KD, Zeilman P, Okun MS. Dyskinetic storm induced by intra-operative deep brain stimulator placement. Open Neurosurg J. 2009;2:1–3
  4. Deuschl G, Herzog J, Kleiner-Fisman G, Kubu C, Lozano AM, Lyons KE, et al. Deep brain stimulation: postoperative issues. Mov Disord. 2006;21(Suppl. 14):S219–S237
  5. Hariz MI. Complications of deep brain stimulation surgery. Mov Disord. 2002;17(Suppl. 3):S162–S166
  6. Hariz MI, Fodstad H. Do microelectrode techniques increase accuracy or decrease risks in pallidotomy and deep brain stimulation? A critical review of the literature. Stereotact Funct Neurosurg. 1999;72:157–169
  7. Binder DK, Rau GM, Starr PA. Risk factors for hemorrhage during microelectrode-guided deep brain stimulator implantation for movement disorders. Neurosurgery. 2005;56:722–732discussion 722–32
  8. Pollak P, Krack P, Fraix V, Mendes A, Moro E, Chabardes S, et al. Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease. Mov Disord. 2002;17(Suppl. 3):S155–S161
  9. Sansur CA, Frysinger RC, Pouratian N, Fu KM, Bittl M, Oskouian RJ, et al. Incidence of symptomatic hemorrhage after stereotactic electrode placement. J Neurosurg. 2007;107:998–1003
  10. Beric A, Kelly PJ, Rezai A, Sterio D, Mogilner A, Zonenshayn M, et al. Complications of deep brain stimulation surgery. Stereotact Funct Neurosurg. 2001;77:73–78
  11. Lyons KE, Wilkinson SB, Overman J, Pahwa R. Surgical and hardware complications of subthalamic stimulation: a series of 160 procedures. Neurology. 2004;63:612–616
  12. Videnovic A, Metman LV. Deep brain stimulation for Parkinson's disease: prevalence of adverse events and need for standardized reporting. Mov Disord. 2008;23:343–349
  13. Gorgulho A, De Salles AA, Frighetto L, Behnke E. Incidence of hemorrhage associated with electrophysiological studies performed using macroelectrodes and microelectrodes in functional neurosurgery. J Neurosurg. 2005;102:888–896
  14. Voges J, Hilker R, Botzel K, Kiening KL, Kloss M, Kupsch A, et al. Thirty days complication rate following surgery performed for deep-brain-stimulation. Mov Disord. 2007;22:1486–1489
  15. Morishita T, Burdick A, Okun MS, Jacobson C, Foote KD. Cerebral venous infarction: an avoidable complication of deep brain stimulation surgery. In: 13th international congress of Parkinson's disease and movement disorders. Paris; 2009.
  16. Umemura A, Jaggi JL, Hurtig HI, Siderowf AD, Colcher A, Stern MB, et al. Deep brain stimulation for movement disorders: morbidity and mortality in 109 patients. J Neurosurg. 2003;98:779–784
  17. Kipps CM, Fung VS, Grattan-Smith P, de Moore GM, Morris JG. Movement disorder emergencies. Mov Disord. 2005;20:322–334
  18. Factor SA, Molho ES. Emergency department presentations of patients with Parkinson's disease. Am J Emerg Med. 2000;18:209–215
  19. Herzog J, Pinsker M, Wasner M, Steigerwald F, Wailke S, Deuschl G, et al. Stimulation of subthalamic fibre tracts reduces dyskinesias in stn-dbs. Mov Disord. 2007;22:679–684
  20. Kenney C, Simpson R, Hunter C, Ondo W, Al maguer M, Davidson A, et al. Short-term and long-term safety of deep brain stimulation in the treatment of movement disorders. J Neurosurg. 2007;106:621–625
  21. Rodriguez RL, Fernandez HH, Haq I, Okun MS. Pearls in patient selection for deep brain stimulation. Neurologist. 2007;13:253–260
  22. Anderson VC, Burchiel KJ, Hogarth P, Favre J, Hammerstad JP. Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease. Arch Neurol. 2005;62:554–560
  23. Okun MS, Fernandez HH, Wu SS, Kirsch-Darrow L, Bowers D, Bova F, et al. Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: the compare trial. Ann Neurol. 2009;
  24. Okun MS, Green J, Saben R, Gross R, Foote KD, Vitek JL. Mood changes with deep brain stimulation of stn and gpi: results of a pilot study. J Neurol Neurosurg Psychiatry. 2003;74:1584–1586
  25. Hariz MI, Rehncrona S, uinn NPQ, Speelman JD, Wensing C. Multicenter study on deep brain stimulation in Parkinson's disease: an independent assessment of reported adverse events at 4 years. Mov Disord. 2008;23:416–421
  26. Tune LE, Damlouji NF, Holland A, Gardner TJ, Folstein MF, Coyle JT. Association of postoperative delirium with raised serum levels of anticholinergic drugs. Lancet. 1981;2:651–653
  27. Poewe W. When a Parkinson's disease patient starts to hallucinate. Pract Neurol. 2008;8:238–241
  28. Frucht SJ. Movement disorder emergencies in the perioperative period. Neurol Clin. 2004;22:379–387
  29. Poston KL, Frucht SJ. Movement disorder emergencies. J Neurol. 2008;255(Suppl. 4):2–13
  30. Foncke EMJ, Schuurman PR, Speelman JD. Suicide after deep brain stimulation of the internal globus pallidus for dystonia. Neurology. 2006;66:142–143
  31. Burkhard PR, Vingerhoets FJG, Berney A, Bogouss lavsky J, Villemure JG, Ghika J. Suicide after successful deep brain stimulation for movement disorders. Neurology. 2004;63:2170–2172
  32. Doshi PK, Chhaya N, Bhatt MH. Depression leading to attempted suicide after bilateral subthalamic nucleus stimulation for Parkinson's disease. Mov Disord. 2002;17:1084–1085
  33. Voon V, Krack P, Lang AE, Lozano AM, Dujardin K, Schupbach M, et al. A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease. Brain. 2008;131:2720–2728
  34. Okun MS, Rodriguez RL, Mikos A, Miller K, Kellison I, Kirsch-Darrow L, et al. Deep brain stimulation and the role of the neuropsychologist. Clin Neuropsychol. 2007;21:162–189
  35. Ghika J, Villemure JG, Miklossy J, Temperli P, Pralong E, Christen-Zaech S, et al. Postanoxic generalized dystonia improved by bilateral voa thalamic deep brain stimulation. Neurology. 2002;58:311–313
  36. Burton DA, Nicholson G, Hall GM. Anaesthesia in elderly patients with neurodegenerative disorders: special considerations. Drugs Aging. 2004;21:229–242
  37. Resnick AS, Foote KD, Rodriguez RL, Malaty IA, Moll JL, Carden DL, et al. The number and nature of emergency department encounters in patients with deep brain stimulators. J Neurol, in press. doi:10.1007/s00415-009-5343-8. Published online 8 October 2009.
  38. Deogaonkar A, Avitsian R, Henderson JM, Schubert A. Venous air embolism during deep brain stimulation surgery in an awake supine patient. Stereotact Funct Neurosurg. 2005;83:32–35
  39. Hooper AK, Okun MS, Foote KD, Haq IU, Fernandez HH, Hegland D, et al. Venous air embolism in deep brain stimulation. Stereotact Funct Neurosurg. 2009;87:25–30
  40. Sillay KA, Larson PS, Starr PA. Deep brain stimulator hardware-related infections: incidence and management in a large series. Neurosurgery. 2008;62:360–366discussion 366–7
  41. Joint C, Nandi D, Parkin S, Gregory R, Aziz T. Hardware-related problems of deep brain stimulation. Mov Disord. 2002;17(Suppl. 3):S175–S180
  42. Kondziolka D, Whiting D, Germanwala A, Oh M. Hardware-related complications after placement of thalamic deep brain stimulator systems. Stereotact Funct Neurosurg. 2002;79:228–233
  43. Oh MY, Abosch A, Kim SH, Lang AE, Lozano AM. Long-term hardware-related complications of deep brain stimulation. Neurosurgery. 2002;50:1268–1274discussion 1274–6
  44. Blomstedt P, Hariz MI. Hardware-related complications of deep brain stimulation: a ten year experience. Acta Neurochir (Wien). 2005;147:1061–1064discussion 1064
  45. Koller W, Pahwa R, Busenbark K, Hubble J, Wilkinson S, Lang A, et al. High-frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor. Ann Neurol. 1997;42:292–299
  46. Miller JP, Acar F, Burchiel KJ. Significant reduction in stereotactic and functional neurosurgical hardware infection after local neomycin/polymyxin application. J Neurosurg. 2009;110:247–250
  47. Okun MS, Rodriguez RL, Foote KD, Sudhyadhom A, Bova F, Jacobson C, et al. A case-based review of troubleshooting deep brain stimulator issues in movement and neuropsychiatric disorders. Parkinsonism Relat Disord. 2008;14:532–538
  48. Geissinger G, Neal JH. Spontaneous twiddler's syndrome in a patient with a deep brain stimulator. Surg Neurol. 2007;68:454–456discussion 456
  49. Yianni J, Nandi D, Shad A, Bain P, Gregory R, Aziz T. Increased risk of lead fracture and migration in dystonia compared with other movement disorders following deep brain stimulation. J Clin Neurosci. 2004;11:243–245
  50. Piacentini S, Romito L, Franzini A, Granato A, Broggi G, Albanese A. Mood disorder following dbs of the left amygdaloid region in a dystonia patient with a dislodged electrode. Mov Disord. 2008;23:147–150
  51. Ellis TM, Foote KD, Fernandez HH, Sudhyadhom A, Rodriguez RL, Zeilman P, et al. Reoperation for suboptimal outcomes after deep brain stimulation surgery. Neurosurgery. 2008;63:754–760discussion 760–1
  52. Krack P, Batir A, Van Blercom N, Chabardes S, Fraix V, Ardouin C, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med. 2003;349:1925–1934
  53. Moreau C, Defebvre L, Destee A, Bleuse S, Clement F, Blatt JL, et al. Stn-dbs frequency effects on freezing of gait in advanced Parkinson disease. Neurology. 2008;71:80–84
  54. Brozova H, Barnaure I, Alterman RL, Tagliati M. Stn-dbs frequency effects on freezing of gait in advanced Parkinson disease. Neurology. 2009;72:770;author reply 770–1
  55. Low HL, Sayer FT, Honey CR. Pathological crying caused by high-frequency stimulation in the region of the caudal internal capsule. Arch Neurol. 2008;65:264–266
  56. Okun MS, Raju DV, Walter BL, Juncos JL, DeLong MR, Heilman K, et al. Pseudobulbar crying induced by stimulation in the region of the subthalamic nucleus. J Neurol Neurosurg Psychiatry. 2004;75:921–923
  57. Kumar R, Krack P, Pollak P. Transient acute depression induced by high-frequency deep-brain stimulation. N Engl J Med. 1999;341:1003–1004author reply 1004
  58. Blomstedt P, Hariz MI, Lees A, Silberstein P, Limousin P, Yelnik J, et al. Acute severe depression induced by intraoperative stimulation of the substantia nigra: a case report. Parkinsonism Relat Disord. 2008;14:253–256
  59. Bejjani BP, Damier P, Arnulf I, Thivard L, Bonnet AM, Dormont D, et al. Transient acute depression induced by high-frequency deep-brain stimulation. N Engl J Med. 1999;340:1476–1480
  60. Miyawaki E, Perlmutter JS, Troster AI, Videen TO, Koller WC. The behavioral complications of pallidal stimulation: a case report. Brain Cogn. 2000;42:417–434
  61. Romito LM, Raja M, Daniele A, Contarino MF, Bentivoglio AR, Barbier A, et al. Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease. Mov Disord. 2002;17:1371–1374
  62. Krack P, Kumar R, Ardouin C, Dowsey PL, McVicker JM, Benabid AL, et al. Mirthful laughter induced by subthalamic nucleus stimulation. Mov Disord. 2001;16:867–875
  63. Bejjani BP, Dormont D, Pidoux B, Yelnik J, Damier P, Arnulf I, et al. Bilateral subthalamic stimulation for Parkinson's disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance. J Neurosurg. 2000;92:615–625
  64. Hariz MI, Johansson F. Hardware failure in parkinsonian patients with chronic subthalamic nucleus stimulation is a medical emergency. Mov Disord. 2001;16:166–168
  65. Hariz MI, Shamsgovara P, Johansson F, Hariz G, Fodstad H. Tolerance and tremor rebound following long-term chronic thalamic stimulation for parkinsonian and essential tremor. Stereotact Funct Neurosurg. 1999;72:208–218
  66. Mariotti P, Fasano A, Contarino MF, Della Marca G, Piastra M, Genovese O, et al. Management of status dystonicus: our experience and review of the literature. Mov Disord. 2007;22:963–968
  67. Vaamonde J, Narbona J, Weiser R, Garcia MA, Brannan T, Obeso JA. Dystonic storms: a practical management problem. Clin Neuropharmacol. 1994;17:344–347
  68. Manji H, Howard RS, Miller DH, Hirsch NP, Carr L, Bhatia K, et al. Status dystonicus: the syndrome and its management. Brain. 1998;121(Pt. 2):243–252
  69. Dalvi A, Fahn S, Ford B. Intrathecal baclofen in the treatment of dystonic storm. Mov Disord. 1998;13:611–612
  70. Elkay M, Silver K, Penn RD, Dalvi A. Dystonic storm due to batten's disease treated with pallidotomy and deep brain stimulation. Mov Disord. 2009;24:1048–1053
  71. Teive HA, Munhoz RP, Souza MM, Antoniuk SA, Santos ML, Teixeira MJ, et al. Status dystonicus: study of five cases. Arq Neuropsiquiatr. 2005;63:26–29

 The review of this paper was entirely handled by the Co-Editor-in-Chief, Zbigniew Wszolek.

PII: S1353-8020(09)00235-1

doi: 10.1016/j.parkreldis.2009.10.003

Parkinsonism & Related Disorders
Volume 16, Issue 3 , Pages 153-162 , March 2010