Parkinsonism & Related Disorders
Volume 16, Issue 7 , Pages 475-477 , August 2010

The impact of and the factors associated with drooling in Parkinson's disease

  • Joshua Leibner

      Affiliations

    • College of Medicine, University of Florida, Gainesville, FL, USA
  • ,
  • Amit Ramjit

      Affiliations

    • College of Medicine, University of Florida, Gainesville, FL, USA
  • ,
  • Laura Sedig

      Affiliations

    • College of Medicine, University of Florida, Gainesville, FL, USA
  • ,
  • Yunfeng Dai

      Affiliations

    • Department of Epidemiology and Health Policy Research, University of Florida, Gainesville, FL, USA
  • ,
  • Samuel S. Wu

      Affiliations

    • Department of Epidemiology and Health Policy Research, University of Florida, Gainesville, FL, USA
  • ,
  • Charles Jacobson IV

      Affiliations

    • Department of Neurology, College of Medicine, University of Florida, Gainseville, FL, USA
  • ,
  • Michael S. Okun

      Affiliations

    • Department of Neurology, College of Medicine, University of Florida, Gainseville, FL, USA
  • ,
  • Ramon L. Rodriguez

      Affiliations

    • Department of Neurology, College of Medicine, University of Florida, Gainseville, FL, USA
  • ,
  • Irene A. Malaty

      Affiliations

    • Department of Neurology, College of Medicine, University of Florida, Gainseville, FL, USA
  • ,
  • Hubert H. Fernandez

      Affiliations

    • Department of Neurology, College of Medicine, University of Florida, Gainseville, FL, USA
    • Corresponding Author InformationCorresponding author at: Department of Neurology, University of Florida, Rm L3-100, McKnight Brain Institute, 100 S. Newell Drive, Gainesville, FL 32610, USA. Tel.: +1 352 273 5550; fax: +1 352 273 5575.

Received 3 July 2009 ,Revised 30 November 2009 ,Accepted 3 December 2009.

References 

  1. Johnston BT, Li Q, Castell JA, Castell DO. Swallowing and esophageal function in Parkinson's disease. American Journal of Gastroenterology. 1995;90:1741–1746
  2. Bagheri H, Damase-Michel C, Lapeyre-Mestre M, Cismondo S, O’Connell D, Senard JM, et al. A study of salivary secretion in Parkinson's disease. Clinical Neuropharmacology. 1999;22:213–215
  3. Kalf JG, Smit AM, Bloem BR, Zwarts MJ, Munneke M. Impact of drooling in Parkinson's disease. Journal of Neurology. 2007;254:1227–1232
  4. Clarke CE, Gullaksen E, Macdonald S, Lowe F. Referral criteria for speech and language therapy assessment of dysphagia caused by idiopathic Parkinson's disease. Acta Neurologica Scandinavica. 1998;97:27–35
  5. Nilsson H, Ekberg O, Olsson R, Hindfelt B. Quantitative assessment of oral and pharyngeal function in Parkinson's disease. Dysphagia. 1996;11:144–150
  6. Proulx M, de Courval FP, Wiseman MA, Panisset M. Salivary production in Parkinson's disease. Movement Disorders. 2005;20:204–207
  7. Lloret SP, Arce GP, Rossi M, Nemet MLC, Salsamendi P, Merello M. Validation of a new scale for the evaluation of sialorrhea in patients with Parkinson's disease. Movement Disorders. 2007;22:107–111
  8. Gibb WRG, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. Journal of Neurology, Neurosurgery & Psychiatry. 1988;51:745–752
  9. Davydov I, Botts SR. Clozapine-induced hypersalivation. The Annals of Pharmacotherapy. 2000;34:662–665

 The review of this paper was entirely handled by an Associate Editor, Rober Rodnitzky.

PII: S1353-8020(09)00306-X

doi: 10.1016/j.parkreldis.2009.12.003

Parkinsonism & Related Disorders
Volume 16, Issue 7 , Pages 475-477 , August 2010