Parkinsonism & Related Disorders
Volume 16, Issue 7 , Pages 466-470 , August 2010

Affective and cognitive theory of mind in patients with parkinson’s disease

  • Maren E. Bodden

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • ,
  • Brit Mollenhauer

      Affiliations

    • Paracelsus-Elena-Hospital, Kassel, Germany
    • Georg August University, Göttingen, Germany
    • ,
  • Claudia Trenkwalder

      Affiliations

    • Paracelsus-Elena-Hospital, Kassel, Germany
    • Georg August University, Göttingen, Germany
    • ,
  • Nicole Cabanel

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • ,
  • Karla Maria Eggert

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • ,
  • Marcus Michael Unger

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • ,
  • Wolfgang Hermann Oertel

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • ,
  • Josef Kessler

      Affiliations

    • Department of Neurology, University of Cologne, Cologne, Germany
    • ,
  • Richard Dodel

      Affiliations

    • Department of Neurology, Philipps-University Marburg, Marburg, Germany
    • Corresponding Author InformationCorresponding author. Department of Neurology, Philipps-University Marburg, Rudolf-Bultmannstr. 8, D-35039 Marburg, Germany. Tel.: +49 6421 5866251; fax: +49 6421 5865474.
    • ,
  • Elke Kalbe

      Affiliations

    • Department of Gerontology, University of Vechta, Vechta, Germany
    • Department of Neurology, University of Cologne, Cologne, Germany
    • Cognitive Neurology Section (INM-3), Research Centre Juelich, Germany

Received 17 September 2009 ,Revised 24 February 2010 ,Accepted 27 April 2010.

References 

  1. Caballol N, Marti MJ, Tolosa E. Cognitive dysfunction and dementia in Parkinson disease. Mov Disord. 2007;22(Suppl. 17):358–366
  2. Poewe W. Non-motor symptoms in Parkinson’s disease. Eur J Neurol. 2008;15(Suppl. 1):14–20
  3. Zgaljardic DJ, Borod JC, Foldi NS, Mattis PJ, Gordon MF, Feigin A, et al. An examination of executive dysfunction associated with frontostriatal circuitry in Parkinson’s disease. J Clin Exp Neuropsychol. 2006;28(7):1127–1144
  4. Mengelberg A, Siegert RJ. Is theory-of-mind impaired in Parkinson’s disease?. Cogn Neuropsychiatry. 2003;8(3):191–209
  5. Péron J, Vicente S, Leray E, Drapier S, Drapier D, Cohen R, et al. Are dopaminergic pathways involved in theory of mind? A study in Parkinson’s disease. Neuropsychologia. 2009;47:406–414
  6. Saltzman J, Strauss E, Hunter M, Archibald S. Theory of mind and executive functions in normal human aging and Parkinson’s disease. J Int Neuropsychol Soc. 2000;6(7):781–788
  7. Yoshimura N, Kawamura M, Masaoka Y, Homma I. The amygdala of patients with Parkinson’s disease is silent in response to fearful facial expressions. Neuroscience. 2005;131:523–534
  8. Frith CD, Frith U. Interacting minds-a biological basis. Science. 1999;286(5445):1692–1695
  9. Adolphs R. Social cognition and the human brain. Trends Cogn Sci. 1999;3(12):469–479
  10. Amodio DM, Frith CD. Meeting of minds: the medial frontal cortex and social cognition. Nat Rev Neurosci. 2006;7(4):268–277
  11. Siegal M, Varley R. Neural systems involved in “theory of mind”. Nat Rev Neurosci. 2002;3(6):463–471
  12. Kalbe E, Grabenhorst F, Brand M, Kessler J, Hilker R, Markowitsch HJ. Elevated emotional reactivity in affective but not cognitive components of theory of mind: a psychophysiological study. J Neuropsychol. 2007;1:27–38
  13. Hynes CA, Baird AA, Grafton ST. Differential role of the orbital frontal lobe in emotional versus cognitive perspective-taking. Neuropsychologia. 2006;44(3):374–383
  14. Völlm BA, Taylor AN, Richardson P, Corcoran R, Stirling J, McKie S, et al. Neuronal correlates of theory of mind and empathy: a functional magnetic resonance imaging study in a nonverbal task. Neuroimage. 2006;29(1):90–98
  15. Bodden M, Dodel R, Kalbe E. Theory of mind in Parkinson’s disease and related basal ganglia disorders: a systematic review. Mov Disord. 2010;25(1):13–27
  16. Shamay-Tsoory SG, Aharon-Peretz J. Dissociable prefrontal networks for cognitive and affective theory of mind: a lesion study. Neuropsychologia. 2007;45:3054–3067
  17. Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ. What features improve the accuracy of clinical diagnosis in Parkinson’s disease: a clinicopathologic study. Neurology. 1992;42(6):1142–1146
  18. Goetz CG, Poewe W, Rascol O, Sampaio C, Stebbins GT, Counsell C, et al. Movement disorder society task force report on the Hoehn and Yahr staging scale: status and recommendations. Mov Disord. 2004;19(9):1020–1028
  19. Diener HC, Putzki N, Berlit P. Leitlinien für diagnostik und therapie in der neurologie. 4th ed.. Stuttgart: Georg Thieme Verlag; 2008;
  20. Folstein MF, Folstein SE, Mc Hugh PR. Mini-mental state: a practical method for grading the state of patients for the clinician. J Psychiatr Res. 1975;12:189–198
  21. Kalbe E, Calabrese P, Kohn N, Hilker R, Riedel O, Wittchen HU, et al. Screening for cognitive deficits in Parkinson’s disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument. Parkinsonism Relat Disord. 2008;14(2):93–101
  22. Schaaf A, Kessler J, Grond M, Fink GR. Memo-test. Göttingen: Hogrefe; 1992;
  23. Härting C, Markowitsch HJ, Neufeld U, Calabrese P, Deisinger K, Kessler J. Wechsler Gedächtnis test – revidierte fassung (WMS-R). Bern: Huber; 2000;
  24. Aschenbrenner S, Tucha O, Lange KW. Regensburger Wortflüssigkeits- test. Göttingen: Hogrefe; 2000;
  25. Tombaugh TN. Trail making test A and B: normative data stratified by age and education. Arch Clin Neuropsychol. 2004;19:203–214
  26. Horn W. Leistungsprüfsystem. Göttingen: Hogrefe; 1983;
  27. Hautzinger M, Keller F, Kühner C. BDI-II – beck depressions-inventar – manual. Frankfurt: Harcourt Test Services GmbH; 2006;
  28. Jenkinson C, Fitzpatrick R, Peto V, Greenhall R, Hyman N. The Parkinson’s Disease Questionnaire (PDQ-39): development and validation of a Parkinson’s disease summary index score. Age Ageing. 1997;26(5):353–357
  29. Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I. The “Reading the Mind in the Eyes” Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry. 2001;42(2):241–251
  30. Russell TA, Schmidt U, Doherty L, Young V, Tchanturia K. Aspects of social cognition in anorexia nervosa: affective and cognitive theory of mind. Psychiatry Res. 2009;168:181–185
  31. Kalbe E, Schlegel M, Sack AT, Nowak DA, Dafotakis M, Bangard C, et al. Dissociating cognitive from affective theory of mind: a TMS study. Cortex. 2010;46(6):769–780
  32. Schrag A, Jahanshahi M, Quinn N. What contributes to quality of life in patients with Parkinson’s disease?. J Neurol Neurosurg Psychiatr. 2000;69(3):308–312
  33. Thiel A, Hilker R, Kessler J, Habedank B, Herholz K, Heiss WD. Activation of basal ganglia loops in idiopathic Parkinson’s disease: a PET study. J Neural Transm. 2003;110(11):1289–1301
  34. Dujardin K, Blairy S, Defebvre L, Duhem S, Noel Y, Hess U, et al. Deficits in decoding emotional facial expressions in Parkinson’s disease. Neuropsychologia. 2004;42(2):239–250
  35. Bird CM, Castelli F, Malik O, Frith U, Husain M. The impact of extensive medial frontal lobe damage on ’Theory of Mind’ and cognition. Brain. 2004;127(4):914–928
  36. Perner J, Lang B, Kloo D. Theory of mind and self-control: more than a common problem of inhibition. Child Dev. 2002;73(3):752–767
  37. Channon S, Sinclair E, Waller D, Healey L, Robertson MM. Social cognition in Tourette’s syndrome: intact theory of mind and impaired inhibitory functioning. J Autism Dev Disord. 2004;34(6):669–677
  38. Cuerva AG, Sabe L, Kuzis G, Tiberti C, Dorrego F, Starkstein SE. Theory of mind and pragmatic abilities in dementia. Neuropsychiatry Neuropsychol Behav Neurol. 2001;14(3):153–158

☆ The review of this paper was entirely handled by an Associate Editor, Jonathan Carr.

☆☆ Statistical analyses were conducted by E. Kalbe and M. Bodden.

PII: S1353-8020(10)00103-3

doi: 10.1016/j.parkreldis.2010.04.014

Parkinsonism & Related Disorders
Volume 16, Issue 7 , Pages 466-470 , August 2010

Article Tools

* Image Usage & Resolution