Abstract
Previous research on tremor pathophysiology showed that tremor can be affected, e.g.
by electrical stimulation of the peripheral nerve, mechanical perturbation of the
limb and by transcranial magnetic stimulation of the motor cortex. This report is
focused on possible effects of muscle vibration (MV) on resting tremor in Parkinson's
Disease (PD). Vibratory stimulation was applied to the tendons of M. extensor carpi
radialis longus and M. flexor ulnaris in 27 subjects with moderate PD resting tremor.
The following effects were observed: (1) tremor stopped or started time-locked to
MV onset and offset, (2) tremor persisted during MV but its frequency pattern changed.
These results are discussed with specific emphasis to effects of MV on spinal and
supraspinal levels.
Keywords
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Article info
Publication history
Accepted:
April 10,
2001
Received in revised form:
April 7,
2001
Received:
April 24,
2000
Identification
Copyright
© 2002 Elsevier Science Ltd. Published by Elsevier Inc. All rights reserved.