Short communication| Volume 20, ISSUE 11, P1290-1292, November 2014

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Concomitant development of hypersexuality and delusional jealousy in patients with Parkinson's disease: A case series

Published:September 18, 2014DOI:


      • We investigated concomitant DJ and ICDs in PD.
      • We found preliminary evidence of an association between DJ and hypersexuality.
      • DJ and hypersexuality may reflect a common alteration of sexuality.
      • Sexuality should be investigated when features of either one of them appear.



      Both impulse-control disorders and delusional jealousy (DJ) may be considered non-motor side-effects of dopamine agonist therapy in Parkinson's disease (PD). We aimed to investigate the possible concomitant development of these features in PD and their clinical correlates.


      We performed a cross-sectional investigation in 1063 consecutive PD patients with the Questionnaire for Impulsive Compulsive Disorders in Parkinson's disease and the Parkinson's Psychosis Questionnaire.


      81 patients presented ICDs (prevalence 7.61%) and 23 patients presented DJ (17 males, 6 females; prevalence 2.16%). 9 male PD patients presented both DJ and ICDs (39.13% of patients with DJ, 11.11% of patients with ICDs; prevalence of 0.84% in the whole PD sample), with a concomitant onset of delusional jealousy and hypersexuality in 8 cases and a concomitant onset of delusional jealousy and pathological gambling in 2 cases.


      Hypersexuality and delusional jealousy may occur independently in PD patients “on” dopamine agonist therapy, but may develop together probably reflecting a common alteration of sexuality (sexual arousal and jealousy) The presence of both of these clinical features and sexuality more in general should be investigated when features of either one of them appear. Further confirmation is needed in larger samples of patients.


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