One of the most recent technological advances in deep brain stimulation (DBS) technology
has been the introduction of axial current steering. Until now, the electrical field
could only be shaped along the lead axis. Two intraoperative studies with novel lead
designs revealed larger therapeutic windows with directional DBS [
1
,
2
], most probably due to the reduction of inadvertent current spread to structures surrounding
the stimulation target. DBS leads with two levels of tripartite electrodes capable
of conventional circular stimulation (by simultaneous activation of all segments)
as well as axial current steering have recently become commercially available for
permanent implantation. In a pilot study, an expansion of the therapeutic window using
directional stimulation with these leads could be demonstrated [
[3]
].- Steigerwald F.
- Müller L.
- Johannes S.
- Matthies C.
- Volkmann J.
Directional deep brain stimulation of the subthalamic nucleus: a pilot study using
a novel neurostimulation device.
Mov. Disord. 2016; (n/a-n/a)https://doi.org/10.1002/mds.26669
Keywords
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References
- Directional deep brain stimulation: an intraoperative double-blind pilot study.Brain. 2014; 137: 2015-2026https://doi.org/10.1093/brain/awu102
- Directional steering: a novel approach to deep brain stimulation.Neurology. 2014; 83: 1163-1169https://doi.org/10.1212/WNL.0000000000000823
- Directional deep brain stimulation of the subthalamic nucleus: a pilot study using a novel neurostimulation device.Mov. Disord. 2016; (n/a-n/a)https://doi.org/10.1002/mds.26669
- Tremor response to polarity, voltage, pulsewidth and frequency of thalamic stimulation.Neurology. 2003; 60: 786-790
Article info
Publication history
Published online: August 11, 2016
Received:
May 24,
2016
Identification
Copyright
© 2016 Elsevier Ltd. All rights reserved.
