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Kinematic assessment of bradykinesia due to focal basal ganglia lesions: a series of two ischemic stroke cases

Published:September 29, 2022DOI:https://doi.org/10.1016/j.parkreldis.2022.09.017

      Highlights

      • We report two cases of unilateral parkinsonism due to ischemic basal ganglia lesions.
      • The lesions involved the substantia nigra in Case 1 and the striatum in Case 2.
      • We assessed bradykinesia in patients with an optoelectronic motion system.
      • We found that bradykinesia had different features in relation to lesion topography.
      • Our finding may contribute to current hypotheses on bradykinesia pathophysiology.

      Keywords

      Abbreviations:

      (BG) (basal ganglia), (CT) (computed tomography), (HCs) (healthy controls), (MDS-UPDRS) (Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale), (MRI) (magnetic resonance imaging), (NIHSS) (National Institutes of Health Stroke Scale), (PD) (Parkinson's disease), (SD) (standard deviation), (SN) (substantia nigra)
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