- •We report two cases of unilateral parkinsonism due to ischemic basal ganglia lesions.
- •The lesions involved the substantia nigra in Case 1 and the striatum in Case 2.
- •We assessed bradykinesia in patients with an optoelectronic motion system.
- •We found that bradykinesia had different features in relation to lesion topography.
- •Our finding may contribute to current hypotheses on bradykinesia pathophysiology.
Abbreviations:(BG) (basal ganglia), (CT) (computed tomography), (HCs) (healthy controls), (MDS-UPDRS) (Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale), (MRI) (magnetic resonance imaging), (NIHSS) (National Institutes of Health Stroke Scale), (PD) (Parkinson's disease), (SD) (standard deviation), (SN) (substantia nigra)
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
- The behavioural and motor consequences of focal lesions of the basal ganglia in man.Brain. 1994; 117: 859-876
- Movement disorders in cerebrovascular disease.Lancet Neurol. 2013; 12: 597-608https://doi.org/10.1016/S1474-4422(13)70057-7
- Localizing parkinsonism based on focal brain lesions.Brain. 2018; 141: 2445-2456https://doi.org/10.1093/brain/awy161
- Evolving concepts on bradykinesia.Brain. 2020; 143: 727-750https://doi.org/10.1093/brain/awz344
- Bradykinesia in early and advanced Parkinson's disease.J. Neurol. Sci. 2016; 369: 286-291https://doi.org/10.1016/j.jns.2016.08.028
- Emerging concepts on bradykinesia in non-parkinsonian conditions.Eur. J. Neurol. 2021; https://doi.org/10.1111/ene.14851
- Unilateral parkinsonism following a large infarct in the territory of the lenticulostriate arteries.Mov. Disord. 1997; 12: 1086-1090https://doi.org/10.1002/mds.870120642