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The plight of loneliness in Parkinson's disease: New opportunities

      Highlights

      • Loneliness has been increasing in prominence and individuals with Parkinson's disease (PD) are not unscathed.
      • Loneliness is cross-sectionally related to, and longitudinally precedes, motor, cognitive, and emotional decline.
      • The authors summarize current work in PD and advocate for clinicians' awareness and researchers' investigational focus.

      Abstract

      The human phenomenon of loneliness has been increasing in prominence across societies, with precipitous increase since COVID-19, and individuals with Parkinson's disease are not unscathed. Loneliness is of clinical relevance as it is cross-sectionally related to, and longitudinally precedes, mortality and other health risks, including worse motor, cognitive, and behavioral-psychological functioning. Relatively few studies have evaluated loneliness, or associated social experiences, in the context of Parkinson's, but the existing data is provocative. The authors advocate for clinicians' awareness and researchers' investigational focus.

      Keywords

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